神经纤维瘤病 (ｎｅｕｒｏｆｉｂｒｏｍａｔｏｓｉｓ)好发于头面部 ,因其所具有的组织学特点 ,早期手术切除是唯一有效的治疗方法。对于巨大的头皮神经纤维瘤病 ,临床上处理起来较为棘手 ,我们采用预置扩张器 ,一次手术切除病灶并修复缺损 ,取得了良好的效果 ,治疗经验总结如下 Neurofibromatosis occurs predominantly on the face and head. Because of its histological features, early surgical resection is the only effective treatment. For the huge scalp neurofibromatosis, it is clinically difficult to handle. We use a preset dilator to remove the lesion and repair the defect once, and achieved good results. The treatment experience is summarized as follows: