目的 :通过对CZES型防反流食管支架远期疗效的研究 ,全面评价CZES型防反流型食管支架的性能。方法 :对 2 8例随访超过 2年的放置防反流食管支架患者随访临床症状 ,胃镜下观察防反流瓣的逆向开启和顺向复位运动状况 ;监测 2 4h后取出的防反流食管支架 ,检测防反流瓣的逆向开启压 ,同时检测新出厂的防反流食管支架的防反流瓣的逆向开启压 ,并进行比较。结果 :2 8例患者均无反流性食管炎症状 ,胃镜检查见防反流瓣膜因呕吐而逆向开启 ,因胃舒张而顺向复位 ,2 4h食管pH值检测无胃酸反流。支架放置 2年后与刚放置时无明显差异 ;7例取出的支架 ,防反流瓣膜的逆向开启压与新出厂的支架无显著差异。结论 :CZES型防反流食管支架的防反流瓣膜在正常胃压力下能防止胃酸反流 ,在胃内压增高时通逆向开启而发生呕吐并迅速自动复位。防反流瓣膜能持久保持良好的物理性能 ,近远期均具有类似贲门的功能 OBJECTIVE: To evaluate the long-term efficacy of CZES anti-reflux esophageal stent in comprehensive evaluation of CZES anti-reflux esophageal stent. Methods: Twenty-eight cases of patients with esophageal reflux esophageal stent were followed up for more than 2 years. Gastroscopy was used to observe the anti-reflux flap’s reverse opening and forward movement. The anti-reflux esophageal stent was removed after 24 hours, Reverse anti-reflux valve to detect the anti-open pressure, while testing the new anti-reflux esophageal stent anti-reflux valve reverse cracking pressure, and compared. RESULTS: Twenty-eight patients had no symptoms of reflux esophagitis. Gastroscopy revealed that the anti-reflux valve was reversely opened due to vomiting, and was anorexia due to gastric relaxation. There was no acid reflux in the 24 h esophageal pH test. There was no significant difference between 2-year stent placement and just placement. There was no significant difference between stent-graft and anti-reflux valve in 7 cases with the new stent. CONCLUSIONS: Anti-reflux valves of CZES anti-reflux esophageal stents prevent gastric acid reflux under normal gastric pressure and vomit and vomit quickly and automatically when the intragastric pressure is increased reversely. Anti-reflux valve can maintain long-term good physical properties, near and far have similar cardiac function