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为了更详细准确地掌握人和实验动物涎腺在正常组织结构上的差异,使在选择动物模型进行涎腺研究时更具科学性,我们首次采用图象分析仪,系统地检测比较了8 种实验动物和人正常涎腺腺泡的大小和腺体内各组织成分的平均体积比。结果发现:人和猴的3 种腺体的腺泡大小无明显差异;除兔以外,人的腮腺腺泡最小;人的颌下腺腺泡大于啮齿类动物的颌下腺腺泡而小于其它动物的;除兔的舌下腺腺泡明显较小,羊的舌下腺腺泡明显较大外,其它动物与人无明显差异。粘液腺泡大于浆液和浆粘液腺泡。人体腮腺中腺泡明显少于其它动物,而间质较多;啮齿类动物颌下腺中导管系统的平均体积比远高于其它动物;舌下腺中,啮齿类动物的腺泡较多而间质较少,别的动物各组织成分差别不大。
In order to more accurately and accurately grasp the difference of normal tissue between human and experimental salivary glands, it is more scientific when choosing animal model for salivary gland research. For the first time, we use image analyzer to systematically test and compare 8 kinds of salivary glands Experimental animals and human normal salivary gland acini size and the average volume ratio of each component of the gland. The results showed that there was no significant difference in the size of acinar between the three glands of human and monkey; except for rabbit, the parotid gland of the human was the smallest; the human submandibular gland acinar was smaller than that of the rodent submandibular gland; Rabbit sublingual acinar was significantly smaller, sheep subepithelial acinar was significantly larger, other animals and no significant difference. Mucus acinar is larger than the slurry and mucus mucus. The acinar in the parotid gland of the human body is significantly less than other animals, while the interstitial is more; the average volume ratio of the ductal system in the submandibular gland of rodents is much higher than that of other animals; in the sublingual glands, rodents have more acini and interstitial Less, other animals, the composition of the little difference.