虽然近期的一些文章将应激这一概念的渊源上溯到贝尔纳（Ｂｅｒｎａｒｄ）的内环境及其恒定及坎农（Ｃａｏｎｏｎ）“稳态”概念与“应激学说”问世之时，但是，当前应激学说的主体理论还是以塞里（Ｓｅｌｙｅ）的“一般适应综合征”（ＧＡＳ）及“垂体－肾上腺皮质轴”（现在加上下丘? Although recent sources have traced the origins of the concept of stress to Bernard’s internal environment and its constancy and Caonon’s notion of “steady state” and the advent of “stress theory” However, the principal theory of the present stress theory is based on Selye’s general adaptive syndrome (GAS) and the pituitary-adrenal axis (now plus the inferior colliculus)