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对18例无胆红素脑病表现的高胆红素血症新生儿的啼哭信号进行了声谱分析.结果显示,患儿的基频各值、第一共振频率变异值及双音百分比高于正常,第一共振频率最小值低于正常.基频各值及第一共振频率变异值的改变与胆红素水平值呈正相关关系.本结果说明在非胆红素脑病状态下,胆红素对中枢神经系统具有早期毒性作用。
Eighteen patients with hyperbilirubinaemia who did not show bilirubin encephalopathy were analyzed by cryptic signals.The results showed that the values of the fundamental frequency, the first resonance frequency and the percentage of double-syllable frequency were higher Normal, the first resonance frequency is lower than the normal minimum.Variable value of the fundamental frequency and the first resonance frequency changes and bilirubin levels were positively correlated.The results show that in the non-bilirubin encephalopathy state, bilirubin Has early toxic effects on the central nervous system.