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葛花解醒口服液对低剂量乙醇中毒引起的小鼠中枢神经系统兴奋，有明显的抑制作用，而对高剂量乙醇中毒引起的大鼠与小鼠中枢神经系统抑制现象，则有一定对抗性。可有效地缩短小鼠穿越水迷宫的时间，还可增加硝酸士的宁与电刺激致小鼠惊厥的存活率。
Gehua Jiexuan Oral Liquid has a significant inhibitory effect on the central nervous system excitability in mice induced by low-dose ethanol poisoning, while there is a certain degree of resistance to the inhibition of central nervous system in rats and mice caused by high-dose ethanol poisoning. . It can effectively shorten the time of mice crossing the water maze, and increase the survival rate of strychnine induced by strychnine and electrical stimulation in mice.