异名 Xanax,U31889,TUS-1 化学名 8-氯-1-甲基-6-苯基-4H-1,2,4-三唑并[4,3-a][1,4]苯并二氮杂(艹卓) 药效分类安定药开发单位 (美)Upjohn 上市厂商 (美)Upjohn 1981年11月首次报道 Pharmacologist 13∶234,1971 药理本品为新的苯并二氮杂(艹卓)类似物。在胃肠道中吸收迅速;给药后1～2小时达血峰浓度。药物大部分被代谢,但不生成作用时间长的代谢物。消除半衰期约14小时,与其他短效的苯并二氮杂(艹卓)类药物如氯羟安定(Lorazepam)、去甲羟基安定(Oxa Synonyms Xanax, U31889, TUS-1 Chemical name 8-Chloro-1-methyl-6-phenyl-4H-1,2,4-triazolo [4,3-a] [1,4] Diazepam Pharmacokinetic Assay Drugs Developed by Upjohn Upjohn First Reported in November 1981 Pharmacologist 13:34, 1971 Pharmacology This product is a new benzodiazepine )analog. Rapid absorption in the gastrointestinal tract; 1 to 2 hours after administration peak blood concentration. Most of the drug is metabolized, but does not produce long-acting metabolites. The elimination half-life of about 14 hours, with other short-acting benzodiazepines such as Lorazepam, Oxa