本病于1942年首先由Danbolt氏等所报告,主要发生于婴儿的一种少见的皮肤病,本病原因不明。1953年Dillha氏首先报道用双碘喹啉治疗本病获得成功,使本病在预后不良方面有较大的转折,1973年Bornes氏等报告1例肠病性肢端皮炎,患者血清中锌减低,口服锌后获得显著疗效,在病因和治疗上有了新的发展,现将笔者所见,经用锌剂及转移因子联合治疗报道于后。病例介绍:武××,男,年龄3个月,第一胎,足月顺产。喂牛、母乳,婴儿出生后40 The disease was first reported in 1942 by Danbolt’s et al., Which occurs predominantly in infants with a rare dermatological condition whose cause is unknown. In 1953, Dillha’s first report of success with diiodoquinoline in the treatment of this disease made the disease a big turning point in the prognosis. Bornes et al reported 1 case of enterocolitis in 1973 and the serum zinc was decreased , After oral zinc obtained significant effect, in the etiology and treatment of a new development, now I see, after the combination of zinc agents and transfer factor reported later. Case description: Wu × ×, male, age 3 months, the first child, term full-term. Feed cattle, breast milk, babies after birth 40