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本文报告5例6支动脉阻塞经导管使用微量泵持续灌注尿激酶(56,000单位/小时)溶栓治疗,灌注时间5.5～.58(平均26)小时。阻塞位于髂外动脉2例,其中1例伴同侧股动脉阻塞:髂总和髂外动脉联合受累1例,腘动脉1例;股腘动脉1例。病程1～24(平均9.4)个月,阻塞长度8～25cm(平均15.3cm),开通率达100％。对溶栓后残存狭窄实施PTA3例、血管内放置支架1例:随访2～9(平均5.3)个月,临床效果满意。表明溶栓及介入技术联合治疗应作为治疗外周动脉梗阻性病变的首选方法。本文着重讨论小剂量溶栓方法、技术操作、影响因素、综合治疗原则及远期疗效巩固等。
This article reports 5 cases of 6 arterial occlusion by catheter catheterization urokinase (56,000 units / hour) thrombolytic therapy, perfusion time 5.5 ~ .58 (average 26) hours. Obstruction in the external iliac artery in 2 cases, 1 case with ipsilateral femoral artery obstruction: common iliac and external iliac artery involvement in 1 case, 1 case of popliteal artery; 1 case of femoral artery. Duration of 1 ~ 24 (average 9.4) months, obstruction length 8 ~ 25cm (average 15.3cm), the opening rate of 100%. Thrombolytic residual stenosis in the implementation of PTA in 3 cases, intravascular placement of stent in 1 case: follow-up of 2 to 9 (average 5.3) months, the clinical effect is satisfactory. Show thrombolysis and interventional therapy should be used as the treatment of peripheral arterial occlusive disease the preferred method. This article focuses on low-dose thrombolysis methods, technical operation, influencing factors, the principle of comprehensive treatment and long-term effect of consolidation and so on.