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作用最强的利尿药是有机汞剂,如汞撒利等,但有一定的毒性副作用,而且必须注射,应用不便。因此,近年合成的新利尿药有两个特点,一是结构中不合汞原子(所谓“非汞利尿剂”),二是可以口服。我国医院现已通用的此项新利尿药,有醋唑磺胺(醋氮酰胺,Acetazoleamidum,Diamox、克尿塞(氯散疾,Chlorothiazidum)和双氢克尿塞(Hydro-chlorothiazidum),国内已经生产。后二者的作用性质基本一致,只是双氢克尿塞此克尿塞强10-15倍,剂量和副作用更小而已。
The most effective diuretic is an organic mercury agent, such as mercury sarizal, but has some toxic side effects, and must be injected, inconvenient to use. Therefore, the new diuretics synthesized in recent years have two characteristics, one is the structure of mercury atoms (the so-called “non-mercury diuretic ”), and the second is oral. This new diuretic, which is now commonly used in Chinese hospitals, has been produced domestically with acetazlone (Acetazolamide, Acetazoleamidum, Diamox, Chlorothiazidum and Hydro-chlorothiazidum) The nature of the role of basically the same, but two grams of hydrochlorothiazide strong hydrochlorothiazide 10-15 times the dose and side effects smaller only.