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[目的]分析杭州市拱墅区女性宫颈病变情况,为宫颈癌防治提供参考依据。[方法]2013年采取整群抽样方法对杭州市拱墅区女性11 276名居民入组研究,研究对象行妇科检查,收集脱落细胞标本,标本采用Cellslide膜式液基细胞学检测和TBS分级诊断系统。[结果]2013年液基细胞学检查11 276人,标本满意率达99.05%。液基细胞学检查异常病变包括不能明确意义不典型鳞状细胞(atypical squamous cells of unknown significance,ASCUS)、不除外高度鳞状上皮内病变的不典型鳞状上皮细胞(atypical squamous cells,cannot exclude HSIL,ASC-H)、低度鳞状上皮内病变(low grade squamous intraepithelial lesions,LSIL)、高度鳞状上皮内病变(high grade squamous intraepithelial lesions,HSIL)不典型腺细胞(atypical glandular cells,AGC)共425人,占3.8%。不同年龄组宫颈液基细胞学异常比例差异有统计学意义(χ2=313.036,P=0.000)。宫颈细胞学异常高发人群集中在30~55岁,其中88.40%的ASCUS+ASC-H发生在30~55岁;91.10%的LSIL发生在26~55岁,HSIL全部病例均集中在30~60岁。[结论 ]宫颈细胞学异常高发人群集中在30~55岁,30~55岁的妇女务必常规进行细胞学检查。宫颈液基细胞学检查发现大量癌前病变患者,为制定妇女卫生保健政策提供了科学依据。
[Objective] To analyze the cervical lesions in Gongshu District of Hangzhou City and provide a reference for the prevention and treatment of cervical cancer. [Methods] A total of 11 276 female residents in Gongshu District of Hangzhou City were enrolled in the study by cluster sampling method in 2013. The subjects were examined by gynecology and exfoliated cells were collected. The specimens were examined by Celllide membrane liquid-based cytology and TBS classification system. [Results] In 11 276 liquid-based cytology tests in 2013, the satisfaction rate of specimens was 99.05%. Liquid-based cytology abnormalities include atypical squamous cells of unknown significance (ASCUS), atypical squamous cells, which can not exclude HSIL , ASC-H), low grade squamous intraepithelial lesions (LSIL), high grade squamous intraepithelial lesions (HSIL), atypical glandular cells (AGC) People, accounting for 3.8%. Cervical liquid-based cytological abnormalities in different age groups showed statistically significant differences (χ2 = 313.036, P = 0.000). The majority of patients with abnormal cervical cytology were 30-55 years old, of whom 88.40% had ASCUS + ASC-H occurred in 30-55 years, 91.10% had LSIL in 26-55 years, and all HSIL cases were in 30-60 years . [Conclusion] The majority of patients with abnormal cervical cytology are concentrated in 30 ~ 55 years old. Women of 30 ~ 55 years old must routinely carry out cytological examination. Cervical liquid-based cytology found that a large number of patients with precancerous lesions provide a scientific basis for the development of women’s health care policy.