Melkersson Rosenthal综合征(MRS)即唇舌水肿面瘫综合征,系以周围性面瘫、反复颜面水肿、皱襞(裂纹)舌为特征的综合征。最早由瑞士的Melkersson于1928年描述颜面水肿及面瘫表现,后由德国Rosenthal于1930年描述皱襞舌的特征性表现,至1949年该三联征被命名为Melkersson-Rosenthal Melkersson Rosenthal syndrome (MRS) is a syndrome of lip-tongue edema with facial paralysis characterized by peripheral facial paralysis, repeated facial edema, and wrinkled (cracked) tongue. First described by Melkersson in Switzerland in 1928, facial edema and facial paralysis were described by the German Rosenthal in 1930 to describe the characteristic features of the fold tongue, until 1949 the triad was named Melkersson-Rosenthal