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目的:探讨胃肠外营养在重症颅脑损伤病人治疗中的应用及临床效果。方法:将我院2002年～2006年56例重症颅脑损伤采用胃肠外营养的治疗方法作为营养手段,观察病人的临床治疗效果。结果:本组56例,死亡18例,中重残12例,痊愈26例,伤口感染6例,合并褥疮6例(Ⅱ～Ⅲ度)。应用PN治疗分别在10-20d创口愈合或基本愈合,无骨折延迟愈合和不愈合。并发周围静脉炎6例;血糖升高30例(8.2～18mmol/L),同时伴有尿糖阳性10例(++或+++)。治疗中测定血红蛋白浓度、淋巴细胞计数、转铁血红蛋白、血浆白蛋白。并在治疗前后进行比较,具有显著性差异(P<0.05)。结论:胃肠外营养在重症脑损伤治疗中切实可行,能够提供足够的营养物质,对维护胃肠功能、减少感染、促进神经功能恢复和降低死亡率都有意义。
Objective: To explore the application of parenteral nutrition in the treatment of patients with severe craniocerebral injury and its clinical effect. Methods: From 2002 to 2006 in our hospital 56 cases of severe craniocerebral injury using parenteral nutrition therapy as a means of nutrition to observe the patient’s clinical effect. Results: The group of 56 cases, 18 cases of death, 12 cases of moderate to severe, cured 26 cases, wound infection in 6 cases, 6 cases of bedsore combined (Ⅱ ~ Ⅲ degrees). Application of PN treatment in 10-20d wound healing or basic healing, delayed healing without fracture and nonunion. Six cases of peripheral phlebitis were complicated with hyperglycemia in 30 cases (8.2-18 mmol / L), accompanied by 10 cases of positive urine sugar (++ or +++). Hemoglobin concentration, lymphocyte count, transfer hemoglobin, and plasma albumin were measured during treatment. And compared before and after treatment, with significant differences (P <0.05). Conclusion: Parenteral nutrition is practicable in the treatment of severe brain injury, which can provide enough nutrients to maintain gastrointestinal function, reduce infection, promote neurological recovery and reduce mortality.