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目的探讨肝癌合并脾功能亢进患者肝癌切除合并脾脏切除的临床意义。方法回顾分析2004年3月至2006年1月我科收治的12例患者,分析手术前后肝功能和血小板、白细胞变化情况。结果术后3d患者白细胞由术前的(3.2±1.7)×109/L升至(13.5±5.3)×109/L,血小板由(52.6±23.7)×109/L升至(245.3±94.6)×109/L,脾功能亢进消失,肝脏功能术后1周也基本恢复至术前水平。结论肝癌切除合并脾脏切除是治疗肝癌合并脾功能亢进患者的有效方法。
Objective To investigate the clinical significance of hepatectomy and splenectomy in patients with liver cancer complicated with hypersplenism. Methods A retrospective analysis of 12 patients admitted to our department from March 2004 to January 2006 was performed to analyze the changes of liver function, platelet and leucocyte before and after operation. Results The leukocyte increased from (3.2 ± 1.7) × 109 / L to (13.5 ± 5.3) × 109 / L preoperatively and the platelet increased from (52.6 ± 23.7) × 109 / L to (245.3 ± 94.6) × 109 / L, disappearance of hypersplenism, liver function 1 week after surgery has basically returned to the preoperative level. Conclusion Hepatectomy combined with splenectomy is an effective method for the treatment of patients with hepatocellular carcinoma complicated with hypersplenism.