近十多年来,人们注意到影响脑内单胺活性或代谢的物质对记忆也有明显影响。有人在动物训练后,脑内注射去甲肾上腺素(NE)或多巴胺(DA),加强儿茶酚胺类介质系统的传递功能,24小时之后,动物回忆测试的成绩得到提高;若将5-羟色胺(5-HT)注射到海马中去,则对记忆有损害作用。我们以前的工作曾发现抗胆碱能药物樟柳碱 For more than a decade, people have noticed that substances that affect monoamine activity or metabolism in the brain also have a significant effect on memory. Some people in the animal training, intracerebral injection of norepinephrine (NE) or dopamine (DA), to enhance the catecholaminergic system of the transfer function, 24 hours later, the animal memorization test results improved; if serotonin -HT) injected into the hippocampus, the memory has a detrimental effect. Our previous work has found that the anticholinergic drug anisodine