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PURPOSE: Several articles have reported regression of rectal lymphoma of mucos a-associated lymphoid tissue after anti-Helicobacter pylori therapy. It remain s unclear, however, whether lymphoma of rectal mucosa-associated lymphoid tissu e is related to Helicobacter pylori infection. METHODS: A 60-year-old woman vi sited our hospital with a complaint of hematochezia. On colonoscopy a pale, ulcerated protrusion approximately 3.5 cm in diameter was found in the rectum. Pathologic diagnosis of a biopsy specimen was low-grade mucosa-associated lym phoid tissue lymphoma. The patient received a ten-day course of levofloxacin, a nd the cycle was repeated three times over seven months. RESULTS: Although persi stence of Helicobacter pylori infection was confirmed, the tumor regressed compl etely. CONCLUSION: Our findings in this case suggest that rectal lymphoma of muc osa-associated lymphoid tissue may be related to unknown microorganisms other t han Helicobacter pylori. Levofloxacin may be effective for treatment of rectal l ymphoma of mucosa-associated lymphoid tissue regardless of Helicobacter pylori infection.
PURPOSE: Several articles have reported regression of rectal lymphoma of mucos a-associated lymphoid tissue after anti-Helicobacter pylori therapy. It remains unclear, however, whether lymphoma of rectal mucosa-associated lymphoid tissu e is related to Helicobacter pylori infection. METHODS: A 60-year-old woman vi sited our hospital with a complaint of hematochezia. On colonoscopy a pale, ulcerated highlight approximately 3.5 cm in diameter was found in the rectum. Pathologic diagnosis of a biopsy specimen was low-grade mucosa-associated lym phoid The patient received a ten-day course of levofloxacin, a nd the cycle was repeated three times over seven months. RESULTS: Although persi stence of Helicobacter pylori was wasted, the tumor regressed compl etely. CONCLUSION: Our findings in this case suggest that rectal lymphoma of muc osa-associated lymphoid tissue may be related to unknown microorganisms other t han Helicobacter pylori. Levofloxacin may be ef fective for treatment of rectal l ymphoma of mucosa-associated lymphoid tissue regardless of Helicobacter pylori infection.