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建立了尿中Ｎ－甲基－（３，４－亚甲二氧苯基）－２－丙胺及其代谢物对映体浓度的分析方法。药物经手性衍生化后，于非手性ＧＣ固定相上分离。采用该法测定了大鼠屎中各对映体浓度，结果表明药物及其代谢物均呈立体选择性代谢．
A method for the analysis of enantiomeric concentrations of N-methyl- (3,4-methylenedioxyphenyl) -2-propylamine and its metabolites in urine was established. The drug is chirally derivatized and separated on achiral GC stationary phase. The method was used to determine the concentration of each enantiomer in rat feces, the results show that the drug and its metabolites showed stereoselective metabolism.