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对广州市１９８９年仅有的两家加工纯棉工厂１３２０名工人作研究，发现可吸入性棉尘与总尘浓度、内毒素含量中位数分别为０．７１（０．４１～１．５１）与５．２８（３．０４～１２．３２）ｍｇ／ｍ３，２００７（１２３６～４１００）Ｅｕ／ｍ３；呼吸系统异常的检出率、慢性气管炎及棉尘病患病率分别为：（１）典型星期一症状９．０％，（２）班后ＦＥＶ１下降≥５％为１６．８％，（３）班后ＦＥＶ１下降≥１０％为４．２％，（４）班前ＦＥＶ１小于预计值８０％为６．１％，（５）ＦＥＶ１／ＦＶＣ＜７５％为４．０％，（６）咳嗽和（或）咳痰１８．２％，（７）慢性气管炎１０．９％，（８）棉尘病〔（１）＋（２）〕患病率为１．７％。与对照组比较，上述指标〔不含（８）〕的相对危险度分别为（１）３０．０，（２）１．４．（３）１．７，（４）０．７，（５）１．２，（６）２．２和（７）２．１；除（４）外所有指标均随年龄、接尘工龄和可吸入棉尘见识按尘量的增加而是增加趋势；与此同时，发现血清ＩｇＡ，ＩｇＧ和ＩｇＭ含量高于对照组，而ＡＮＡＥ则低于对照组。
A study of 1320 workers in two processing pure cotton factories in Guangzhou in 1989 found that the median inhalable cotton dust and total dust concentration and endotoxin content were 0.71 (0.41 ~ 1.51 ) And 5.28 (3.04 ~ 12.32) mg / m3 and 2007 (1236 ~ 4100) Eu / m3. The prevalences of respiratory abnormalities, chronic bronchitis and cotton dust were respectively :( 1) a typical Monday symptom of 9.0%; (2) a fall of ≥5% in FEV1 after class was 16.8%; (3) a ≥10% decrease in FEV1 after class was 4.2%; (4) FEV1 before class was less than Estimated 80% was 6.1%; (5) FEV1 / FVC <75% was 4.0%; (6) Cough and / or expectoration was 18.2%; (7) Chronic bronchitis was 10.9% , (8) The prevalence of cotton dust disease (1) + (2) was 1.7%. Compared with the control group, the relative risk of these indicators (excluding (8)] were (1) 30.0, (2) 1.4. (3) 1.7, (4) 0.7, (5) 1.2, (6) 2.2 and (7) 2.1. All indicators except (4) Inhalable cotton dust increased according to the amount of dust but increased. At the same time, serum IgA, IgG and IgM levels were higher than those of the control group, while ANAE was lower than the control group.