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我们在工作中曾遇到1例因氯丙嗪穴注而致手指坏死截指,这是个严重的教训,为引起大家警惕,特报道于下。患儿徐××(住院号25737),男性,5岁。因高热、嗜睡伴惊跳3天于1965年7月4日入院。临床诊断为流行性乙型脑炎(重型),给予复方氯丙嗪臀部肌注等治疗,6天后停药。以后出现失语、吞咽不能、肢体震颤、肌张力增强、四肢屈曲、右腕关节内屈等后遗症。即应用针刺、按摩等治疗,但效果欠佳,四肢震颤加重,乃于8月9日以小剂量氯丙嗪行两侧神门穴位封闭,每穴注射未经稀释之2.5%氯丙嗪溶液0.16毫升(4毫克),每日1次,连注3天,于
We encountered a case of finger necrosis interception due to chlorpromazine point injection in our work. This is a serious lesson. To arouse people’s vigilance, we reported the following. Xu × × children (hospital number 25737), male, 5 years old. Due to high fever, drowsiness with shock 3 days in July 4, 1965 admission. Clinical diagnosis of Japanese encephalitis (heavy), given compound chlorpromazine glucocorticoid intramuscular injection and other treatment, withdrawal after 6 days. After aphasia, swallowing can not, limb tremor, increased muscle tone, limb flexion, wrist flexion and other sequelae. That the application of acupuncture, massage and other treatment, but the effect is poor, extremity tremor aggravate, is on August 9 to a small dose of chlorpromazine line Shenmen points on both sides closed, each injection of 2.5% undiluted chlorpromazine The solution 0.16 ml (4 mg), 1 times a day, even with 3 days, at