论文部分内容阅读
目的探讨老年急性白血病患者院内感染及治疗情况，以期提高治疗水平。方法回顾分析３８例老年急性白血病患者的院内感染发生率、感染部位、危险因素和治疗情况等，并与同期１５７例非老年患者进行比较。结果老年组发生院内感染３０例（７８．９％），高于同期非老年组（９２例，５９．０％）。感染部位以呼吸系统多见（２０例，６２．５％）。危险因素为白细胞减少和化疗。单纯抗生素治疗有效率３１．３％，抗生素加辅助治疗有效率６６．７％，二者相比差异有显著性（Ｐ＜０．０５）。治疗总有效率为５２．５％。结论老年急性白血病患者院内感染发生率高于同期非老年组。抗生素加辅助治疗优于单纯抗生素治疗。控制感染与骨髓缓解有关。
Objective To investigate the nosocomial infection and treatment of elderly patients with acute leukemia in order to improve the treatment level. Methods The incidence of nosocomial infection, site of infection, risk factors and treatment of 38 acute leukemia patients were retrospectively analyzed and compared with 157 non-elderly patients in the same period. Results There were 30 cases (78.9%) of nosocomial infections in the elderly group, which was higher than the non-elderly group (92 cases, 59.0%) in the same period. Infection sites were more common in the respiratory system (20 cases, 62.5%). Risk factors for leukopenia and chemotherapy. The efficiency of antibiotic treatment alone was 31.3%, and the antibiotic plus adjuvant treatment was 66.7%. There was a significant difference between the two (P<0.05). The total effective rate of treatment is 52.5%. Conclusion The incidence of nosocomial infection in elderly patients with acute leukemia was higher than that in the non-elderly group in the same period. Antibiotic plus adjuvant therapy is superior to simple antibiotic therapy. Control of infection is related to bone marrow remission.