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[Objective] The aim was to optimize the ultrasonic-microwave synergistic extraction conditions of total flavonoids from Morus alba L. leaves by exploring the extraction process. [Method] The single factor test was designed to confirm the main factors and the range of levels, then the orthogonal test was designed to confirm the optimized conditions. [Result] The results showed that the optimum conditions were as following: the extraction power of 400 W, material-liquid ratio of 1∶ 10 (W/V), extraction time of 12 min, and the ethanol concentration of 65% (V/V), under which the extraction efficiency of total flavonoids was 3.07%. [Conclusion] The optimum ultrasonic-microwave synergistic extraction conditions of total flavonoids from Morus alba L. was established in the experiment, which is simple, quick, efficient and free of pollution.
[Objective] The aim was to optimize the ultrasonic-microwave synergistic extraction conditions of total flavonoids from Morus alba L. leaves by exploring the extraction process. [Method] The single factor test was designed to confirm the main factors and the range of levels, then the orthogonal test was designed to confirm the optimized conditions. [Result] The results showed that the optimum conditions were as follows: the extraction power of 400 W, material-liquid ratio of 1:10 (W / V), extraction time of 12 min, and the ethanol concentration of 65% (V / V), under which the extraction efficiency of total flavonoids was 3.07%. [Conclusion] The optimum ultrasonic-microwave synergistic extraction conditions of total flavonoids from Morus alba L. was established in the experiment, which is simple, quick, efficient and free of pollution.