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目的和方法：急性心肌梗死（ＡＭＩ）并发心源性休克（ＣＧＳ）病死率高达８０％～１００％，即使成功实施急诊冠状动脉成形术，其病死率仍高达４０％～５０％，因此，药物治疗依然十分重要。我们连续收治两例ＡＭＩ并发重症ＣＧＳ患者，经３～４周超大剂量多巴胺（２０～５０μｇ·ｋｇ－１ｍｉｎ）联合小剂量硝普钠（５～４０μｇ／ｍｉｎ）持续静脉滴注治疗，均抢救成功后痊愈出院，也未产生心律失常和心肌缺血恶化等严重副作用。结果和结论：提示该合用方案对ＡＭＩ并发ＣＧＳ患者能维持动脉血压，增加组织灌注，改善左心室功能，可能是有效和安全的；同时，也积累了一定的临床治疗经验。
OBJECTIVES AND METHODS: The mortality of acute myocardial infarction (AMI) complicated with cardiogenic shock (CGS) was as high as 80% -100%. Even though emergency coronary angioplasty was successfully performed, the case fatality rate was as high as 40% -50%. Therefore, Treatment is still very important. We received two consecutive patients with AMI complicated with severe CGS. After 3 to 4 weeks of continuous intravenous infusion of large doses of dopamine (20 ~ 50μg · kg-1min) and low-dose sodium nitroprusside (5 ~ 40μg / min) After discharge from hospital, nor serious arrhythmia and myocardial ischemia and other serious side effects. RESULTS AND CONCLUSION: It is suggested that this combination regimen may be effective and safe for patients with AMI complicated with CGS to maintain arterial blood pressure, increase tissue perfusion, and improve left ventricular function. At the same time, it has also accumulated some clinical experience.