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目的：探索在血管束植入真皮下血管网（ＳＶＮ）皮片后，皮片的生化改变．方法：在前文我们建立的血管束植入ＳＶＮ皮片动物模型的基础上，研究术后１ｄ～５ｄ实验组和对照组相应部位氧自由基的变化．结果：测定实验组ＳＶＮ皮片的ＭＤＡ含量的平均为（５５．５±０．７）ｍｏｌ／ｇ，对照组的ＭＤＡ平均为（７４．０±０．９）ｍｏｌ／ｇ，Ｐ＜０．０５．实验组ＳＯＤ值平均为（５．０±０．２）μＵ／ｃｅｌｌ，对照组ＳＯＤ值平均为（２．４±０．３）μＵ／ｃｅｌｌ，Ｐ＜０．０５．实验组与对照组的ＭＤＡ和ＳＯＤ均呈正相关关系，相关系数分别为γＥ＝０．８０５，γＣ＝０．９８８．结论：对照组皮片的缺氧损伤比实验组重．知名血管束的植入加速了实验组ＳＶＮ皮片的血运重建过程，减少了ＳＶＮ皮片的缺氧损伤
OBJECTIVE: To explore the biochemical changes of the skin graft after the vascular bundle is implanted into the subdermal vascular network (SVN). Methods: Based on the animal model of SVN skin implanted with vascular bundles, we studied the changes of oxygen free radicals in the corresponding parts of experimental group and control group from 1 day to 5 days after operation. Results: The average content of MDA in experimental SVN skin slices was (55.5 ± 0.7) mol / g and that in control group was (74.0 ± 0.9) mol / g, P <0. 05. The average SOD value in the experimental group was (5.0 ± 0.2) μU / cell, while that in the control group was (2.4 ± 0.3) μU / cell, P <0.05. There was a positive correlation between MDA and SOD in the experimental and control groups, with correlation coefficients of γE = 0.805 and γC = 0.988. Conclusion: The hypoxia injury in the control group was heavier than that in the experimental group. Implantation of a well-known vascular bundle accelerated the process of revascularization of the SVN skin in the experimental group and reduced the hypoxic injury of the SVN skin