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一些流行病学研究证实,血清总胆固醇(TC)和冠心病(CHD)的倾向呈正相关,但也有不同看法。据国外报告,血TC轻度增高者(平均300毫克％),有22％发生主动脉粥样硬化;TC正常者,也有20％可发生主动脉粥样硬化;甚至血TC低于正常者(平均160毫克％),亦可发生此病。我国浙江舟山地区的渔民血清TC普遍较高,而冠心病的患病率却较低。人血TC的水平和动脉粥样硬化的严重性及动脉壁的胆固醇含量之间的关系还不太清楚。已证实高密度脂蛋白-胆固醇(HDL-C)和冠心病呈负相关。关于心肌梗塞患者血TC、HDL-C的动态变化,及心肌梗塞患者血脂水平与冠状动脉狭窄程度的关系,国外已有报导。本试验的目的是观察我国心肌梗塞患者血脂的动态变化,并与健康人比较,以试图了解血TC、HDL-C与动脉粥样硬化程度的关系。
Some epidemiological studies have confirmed that serum total cholesterol (TC) and coronary heart disease (CHD) is positively correlated, but there are different views. According to foreign reports, a slight increase in blood TC (average 300 mg%), 22% of the occurrence of aortic atherosclerosis; TC normal, there are 20% of the occurrence of aortic atherosclerosis; even blood TC is lower than normal An average of 160 mg%), can also occur the disease. China’s fishermen in Zhoushan, Zhejiang Province, serum TC are generally higher, while the prevalence of coronary heart disease is lower. The relationship between the level of human blood TC and the severity of atherosclerosis and the cholesterol content of the arterial wall is unclear. It has been demonstrated that high-density lipoprotein-cholesterol (HDL-C) is negatively correlated with coronary heart disease. On the dynamic changes of blood TC and HDL-C in patients with myocardial infarction, and the relationship between the level of lipid in patients with myocardial infarction and the degree of coronary artery stenosis, foreign reports have been reported. The purpose of this experiment is to observe the dynamic changes of blood lipids in patients with myocardial infarction in our country, and compared with healthy people in an attempt to understand the relationship between blood TC, HDL-C and the degree of atherosclerosis.