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目的分析结核病患者医院感染的临床特点及危险因素,以有效控制感染的发生。方法回顾性分析广西龙潭医院2005—2007年5791例结核病患者医院感染的临床资料。结果1692例患者并发医院感染,感染率为29.22%;感染部位以肺部为主,为67.71%;其次是肺外的呼吸道部份,感染率为24.65%。引起感染的病原菌种类以革兰阴性菌为主,占50.67%。真菌感染也占较大比例,为18.52%,以白色念珠菌为主。感染与年龄、住院时间、侵袭性操作和广谱抗生素、免疫抑制剂的使用等因素有关。结论结核病易导致医院感染,必须加强医院感染的管理,控制易感因素,规范抗生素的使用,以减少医院感染的发生。
Objective To analyze the clinical characteristics and risk factors of nosocomial infection in tuberculosis patients so as to effectively control the occurrence of infection. Methods The clinical data of 5791 tuberculosis patients in Guangxi Longtan Hospital from 2005 to 2007 were retrospectively analyzed. Results 1692 patients were complicated with nosocomial infection, the infection rate was 29.22%. The main infection area was lung, accounting for 67.71%. The second was pulmonary respiratory tract, the infection rate was 24.65%. Gram-negative bacteria were the main pathogens causing infection, accounting for 50.67%. Fungal infection also accounted for a large proportion of 18.52%, mainly Candida albicans. Infection is related to age, length of stay, invasive procedures, broad-spectrum antibiotics and the use of immunosuppressive agents. Conclusion Tuberculosis can easily lead to nosocomial infection. It is necessary to strengthen the management of nosocomial infections, control the susceptible factors and regulate the use of antibiotics to reduce the occurrence of nosocomial infections.