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α干扰素是具有抗病毒和免疫调节作用的生物学调节活性物质,迄今,对慢性乙型肝炎的抗病毒治疗仍以α—基因重组干扰素为主要药物,近年来,国内外报告应用α—干扰素治疗慢性乙型肝炎取得较好的疗效,特别是基因工程干扰素问世并应用于临床,我们采用源于中国人基因重组的基因工程干扰素α—1b治疗30例慢性乙型肝炎患者,效果显著,现将临床资料加以分析报告如下。 1 资料和方法 1.1 病例选择 50例病人全部为住院患者,男43例,女性7例,年龄17～70岁,平均年龄38.8岁。慢性迁延型肝炎12例,慢性活动型肝炎38例。所有病人诊断均符合1990年第六次全国病毒
Alpha interferon is antiviral and immunomodulatory effects of biological regulatory activity of substances, so far, the antiviral treatment of chronic hepatitis B is still a-gene recombinant interferon as the main drug in recent years, the domestic and foreign reports of the application of α- Interferon treatment of chronic hepatitis B to obtain better efficacy, especially the advent of genetically engineered interferon and applied to clinical, we use genetically engineered interferon alpha-1b derived from Chinese gene recombinant treatment of 30 patients with chronic hepatitis B, The effect is significant, now the clinical data to be analyzed as reported below. 1 Materials and Methods 1.1 Case Selection All 50 patients were hospitalized patients, 43 males and 7 females, aged 17 to 70 years, mean age 38.8 years. Chronic persistent hepatitis in 12 cases, 38 cases of chronic active hepatitis. All patient diagnoses are in line with the sixth national virus in 1990