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目的观察胸腔穿刺引流并注入化疗药物治疗恶性胸腔积液的疗效。方法 62例恶性胸腔积液的患者随机分为观察组和对照组,每组31例。分别采用胸腔穿刺引流并局部注入化疗药物治疗和单纯胸腔穿刺放胸水治疗,统计总有效率及生存率。结果治疗4周后,观察组总有效率(87.1%)高于对照组(61.3%),差异有统计学意义(P<0.05)。观察组6个月存率和1年生存率均高于对照组,差异均有统计学意义(P<0.05)。结论胸腔穿刺引流并局部注入化疗药物治疗恶性胸腔积液疗效肯定,相对延长了患者生存期,具有一定的临床应用价值。
Objective To observe the curative effect of thoracentesis and infusion chemotherapy drugs in the treatment of malignant pleural effusion. Methods Sixty-two patients with malignant pleural effusion were randomly divided into observation group and control group, with 31 cases in each group. Thoracentesis and local injection of chemotherapy drugs and pleural puncture and pleural effusion were used respectively to treat the total effective rate and survival rate. Results After 4 weeks of treatment, the total effective rate (87.1%) in the observation group was higher than that in the control group (61.3%), with significant difference (P <0.05). The 6-month survival rate and 1-year survival rate in the observation group were higher than those in the control group, with significant differences (P <0.05). Conclusions Thoracentesis and local injection of chemotherapeutic drugs for the treatment of malignant pleural effusions have a positive curative effect, which can prolong the survival time of the patients and have certain clinical value.