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目的 进一步了解吸入皮质激素对婴幼儿哮喘的治疗作用、副作用等问题。方法 对 170例 1～ 3岁的轻中重度婴幼儿哮喘患儿 ,随机分成两组。治疗组根据病情的严重程度用面罩型筒式储雾罐吸入丙酸倍氯米松 2 5 0～ 75 0 μg/d ;对照组不用吸入激素 ,只给予酮替芬等预防性治疗。 结果 治疗组患儿发作次数、咳嗽、喘息天数均较未经吸入治疗患儿少 ,并未发现明显副作用。结论 各种严重程度的婴幼儿哮喘 ,借助面罩型储雾罐吸入皮质激素每日 2 5 0～ 75 0 μg均能收到较好疗效 ,而且安全。
Objective To further understand the therapeutic effect and side effects of inhaled corticosteroids on infant asthma. Methods One hundred and seventy-seven infants with mild to moderate asthma infants and young children aged 1 to 3 years old were randomly divided into two groups. In the treatment group, beclomethasone dipropionate 250 to 75 0 μg / d was inhaled with a mask-type cartridge in accordance with the severity of the disease. In the control group, no prophylactic treatment was given such as ketotifen. Results The number of seizures, cough and wheezing in treatment group were less than those in children without inhalation, and no obvious side effects were found. Conclusion Various severity of infant asthma, with mask-type aerosol can inhaled cortical hormones daily 250 ~ 75 0 μg can receive a good effect, and safe.