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自从 1 883年 Ringer发现蛙心在不含钙的液体中停止搏动至今 ,Ca2 +在细胞活动中的作用引起了人们广泛的注意。细胞内游离 Ca2 +浓度的改变是细胞生理功能的重要物质基础 ,也是多种受体激动后信号传递过程中的中心环节。随着细胞内游离Ca2 +测定和其它生物化学、生物工程技术的
Since Ringer’s discovery in 1883 that frog hearts stopped pulsing in calcium-free fluids, the role of Ca2 + in cellular activity has drawn much attention so far. Changes in intracellular free Ca2 + concentration is an important material basis for cellular physiological functions, and is also the central link in the process of signal transmission after a variety of receptor activation. With intracellular free Ca2 + determination and other biochemical, bioengineered technologies