组织细胞增生症X是一组多发于小儿少见的疾病.现将1980年1月～1994年12月收治的6例患者报告如下.1 临床资料①一般资料:患儿6例,男3例,女3例.年龄8月～1岁4例,3～3.5岁2例.病程20天～1月3例,4～7月3例.②临床表现:6例中5例反复出现皮疹,时间最短20天,最长7月.4例具有不同程度的发热.5例苍白、乏力.口腔溃疡迁延4月不愈1例.足跟部皮肤溃疡1月1例.头部包块2例,突眼、尿崩1例.肝大右肋下3～7cm5例,脾大左肋下2cm～平脐4例,质硬.胸腹腔大量积液1例.实验室检查:4例 Hb40～80g/L,2例100～110g/L,4例白细胞总数不同程度升高12.8～19.9×10~9/L,1例减少为1.6×19~9/L,l例正常.BPC4例正常,2例67～90×10~9/L.5例取新鲜皮疹印片细胞病理学检查,见一定数量分化良好的组织细胞(59%～86%)1例血性胸水细胞学检查,见大量分化良好的组织细胞(约60%).骨髓象检查4例,呈增 Histocytosis X is a group of multiple rare disease in children now to January 1980 ~ December 1994 were treated 6 cases reported as follows.1 Clinical data ① General Information: 6 cases of children, 3 males, 3 females in age from August to 1 year in 4 cases, 3 to 3.5 years in 2 cases.The duration of 20 days to January in 3 cases, 4 to 7 months in 3 cases.② Clinical manifestations: 6 cases in 5 cases repeated rash, time The shortest 20 days, the longest in July .4 cases have different degrees of fever .5 cases of pale, fatigue .Oral ulcer persistent in April unhealed in 1. heel skin ulcer in January 1. The head mass in 2 cases, Exophthalmos, diabetes insipidus in 1. Cases of liver right right rib 3 ~ 7cm5 cases, splenomegaly left rib 2cm ~ flat umbilical cord in 4 cases, hard, pleural cavity and a large number of effusion in 1. Laboratory tests: 4 cases of Hb40 ~ 80g / L, 2 cases of 100 ~ 110g / L, the total number of 4 leukocytes increased by 12.8 ~ 19.9 × 10 ~ 9 / L in varying degrees, 1 case decreased to 1.6 × 19 ~ 9 / Cases of 67 ~ 90 × 10 ~ 9 / L.5 cases of fresh rashes imprint cytopathological examination, see a number of well-differentiated tissue cells (59% ~ 86%) 1 case of bloody pleural fluid cytology, see a large number of well-differentiated Of the tissue cells (about 60%) .Bone marrow examination in 4 cases, was increased