采用双微电极电压钳制术测定正常及模拟“缺血”时，异丙肾上腺素对绵羊心脏浦肯野纤维起搏离于流的影响。结果：异丙肾上腺素１×１０－６ｍｏｌ／Ｌ显著增加浦肯野纤维起搏离子流幅值；模拟“缺血”使起搏离子流幅值降低，在此基础上，异丙肾上腺素仍增加起搏离子流，但未能恢复到“缺血…前水平。 Dual microelectrode voltage clamp technique was used to determine the effect of isoprenaline on pacemaker flow in sheep heart Purkinje fibers during normal and simulated ischemia. Results: Isoprenaline 1 × 10-6mol / L significantly increased the rate of Purkinje fiber pacemaker ion flow; simulated “ischemia” reduced the pacemaker ion current amplitude. On the basis of this, isoproterenol remained Increased pacing ion flux but failed to return to "ischemic ... pre-level.