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目的分析信阳市新布尼亚病毒实验室检测结果,掌握发热伴血小板减少综合征流行趋势,为该地区发热伴血小板减少综合征综合防治提供参考资料。方法采集临床发热伴血小板减少综合征诊断病例血清标本579份,应用实时荧光RT-PCR技术检测新布尼亚病毒。结果 579份样本中,新布尼亚病毒核酸检测阳性295份,阳性率50.95%;其中商城县阳性率为22.45%,光山县阳性率为7.08%,占总阳性率的比例为44.07%(130/295)和13.90%(41/295)。病例发病集中在4—7月份,布尼亚病毒感染阳性率以61～70岁组最高,各年龄组差异有统计学意义(χ2=20.552,p<0.01)。结论信阳市发热伴血小板减少综合征具有一定的地域性和季节性,大年龄组高发,新布尼亚病毒为其主要病原。
Objective To analyze the laboratory results of New Bunia virus in Xinyang City and master the epidemiological trend of fever with thrombocytopenia syndrome and provide references for the comprehensive prevention and treatment of fever and thrombocytopenia syndrome in this area. Methods A total of 579 serum samples from clinical diagnosis of fever and thrombocytopenia were collected. Nefunya virus was detected by real-time fluorescence RT-PCR. Results Among 579 samples, 295 were positive for neubunavirus, the positive rate was 50.95%. The positive rate in Shangcheng was 22.45%, the positive rate in Guangshan was 7.08%, and the positive rate was 44.07% (130 / 295) and 13.90% (41/295). The incidence of cases was concentrated in April-July. The positive rate of Bunyavirus infection was the highest in the group of 61-70 years old, with significant difference in all age groups (χ2 = 20.552, p <0.01). Conclusion Xinyang fever with thrombocytopenia syndrome has a certain geographical and seasonal, high incidence of large age group, the new Bunyan virus is the main pathogen.