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A number of patients undergoing curative colorectal resection present with loc al recurrences that are not resectable at the time of diagnosis. Whereas these a re predominantly perianastomotic, only a few are primarily anastomotic occurring at the suture line. A 65-year-old female with Dukes B2 adenocarcinoma of the sigmoid colon after a radical left hemicolectomy had further resections with sta pled anastomosis at 12 and 22 months, for primary anastomotic recurrences. She r emains well 54 months after initial surgery. The recurrent cancers were histolog ically similar and showed no features of microsatellite instability. The microen vironment at the anastomosis and the suture material must have contributed to th is unusual course.
A number of patients undergoing curative colorectal resection present with loc al recurrences that are not resectable at the time of diagnosis. Whereas these a re predominantly perianastomotic, only a few are for anastomotic occurring at the suture line. A 65-year-old female with Dukes B2 adenocarcinoma of the sigmoid colon after a radical left hemicolectomy had further resections with sta pled anastomosis at 12 and 22 months, for primary anastomotic recurrences. She r emains well 54 months after initial surgery. The recurrent cancers were histolog similar similiar and showed no features of microsatellite instability. The microen vironment at the anastomosis and the suture material must have contributed to th is unusual course.