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为证明钙通道阻滞剂能改善急性缺血性中风引起病人死亡率和造成的神经损伤,作者对186例急性缺血性中风病人进行了随机双盲对照试验。治疗组病人中风发作后24小时内,每6小时口服尼莫地平30 mg(不能口服者,用鼻导管给药),连续给药28天。对照组服用安慰剂。 4周治疗期间,各种原因引起病人的死亡率,治疗组比对照组明显减少:治疗组为8例(8.6％),对照组为19例(20.4％)。在随后6个月期间,两组中都有8人死亡。根据
To demonstrate that calcium channel blockers can improve patient mortality and neurological damage caused by acute ischemic stroke, a randomized double-blind controlled trial of 186 patients with acute ischemic stroke was performed. Patients in the treatment group were given 30 mg nimodipine every 6 hours (not given orally by the nasal catheter) within 24 hours after the onset of stroke and were given continuous administration for 28 days. Control group took placebo. Four weeks of treatment, various causes of patient mortality, the treatment group significantly reduced compared with the control group: the treatment group was 8 cases (8.6%), the control group was 19 cases (20.4%). During the next six months, eight people were killed in both groups. according to