病例1.男,5岁。因颈部淋巴结病和发热就诊,后又出现皮疹、唇开裂疼痛、双侧结膜炎等诊断为川崎病(KD),经静脉注射免疫球蛋白(IVIG)和大剂量阿司匹林治疗无效。继又发生排尿困难、尿道口发红、手足关节肿胀,肘、踝、胫、掌跖等处红斑基础上2～3mm的角化性丘疹,左膝部融合成斑块表面云母状鳞屑,尿道口红斑脱屑伴有小糜烂面。皮损活检示角化过度和角层内微脓疡,综合临床表现符合Reiter综 Case 1. Male, 5 years old. Due to cervical lymphadenopathy and fever, rash, labial cracking and bilateral conjunctivitis were diagnosed as KD, intravenous immunoglobulin (IVIG) and high-dose aspirin therapy. Followed by dysuria, urinary tract redness, swelling of hands and feet joints, elbows, ankles, tibia, palmoplantar and other erythema on the basis of 2 ~ 3mm keratosis papules, left knee fusion plaque surface mica-like scales, urethra Lipstick spot scaling accompanied by a small erosion surface. Lesions biopsy showed hyperkeratosis and micro-abscess within the horn, the comprehensive clinical manifestations consistent with Reiter comprehensive