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目的 探讨先天性梅毒早期诊断、及时治疗与预后的关系。方法 对 38例经临床、X线检查及梅毒血清学检查确诊的先天性梅毒进行资料分析与随访。结果 正规青霉素治疗后 ,临床痊愈 2 8例 ,好转 8例 ,放弃治疗 2例。 16例获得随访 ,快速血清反应素环状卡片试验 6个月转阴率为 6 2 .5 % ,1岁时转阴率达 81 2 5 % ;血清梅毒螺旋体血凝试验均持续阳性。骨损害于 1岁左右恢复正常。结论 先天性梅毒应早期诊断 ,及时治疗 ,青霉素治疗要足量 ,疗程应正规 ,以免复发。
Objective To explore the early diagnosis of congenital syphilis, timely treatment and prognosis. Methods 38 cases of congenital syphilis diagnosed by clinical, X-ray examination and syphilis serology were analyzed and followed up. Results After treatment with formal penicillin, 28 cases were clinically cured, 8 cases improved, and 2 cases were given up. 16 cases were followed up, the fasting serum cyclic protein card test 6 months, the negative conversion rate of 62.5%, 1 year old negative conversion rate of 81 2 5%; serum syphilis spirochete hemagglutination test were positive. Bone damage at 1 year old returned to normal. Conclusion Congenital syphilis should be diagnosed early, timely treatment, penicillin treatment should be sufficient, the treatment should be formal, so as to avoid recurrence.