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本实验通过墨汁血管灌注法和显微血管造影技术,对33只日本种大耳白兔短期糖皮质激素应用条件下,新鲜异体骨移植的血管重建问题进行了研究,结果表明:①异体骨髓腔侧的血管重建主要是通过邻近宿主骨源性血管的向内生长而实现的。而皮质骨则主要是通过骨内,外膜侧血管的向内穿透及对原哈佛氏血管的再占据而实现的。同时有早期少量与原哈佛氏血管再通的情况存在;②在短期免疫抑制条件下,新鲜异体骨移植与自体骨移植的血管重建速率基本接近、③血管重建是骨形成的先导、血管浸润先于骨生成发生,并调节了成骨过程.不同来源,不同条件下的血管浸润,对骨的生成与吸收可能有不尽相同的影响。
In this study, the ink-vascular perfusion and microvascular angiography, 33 Japanese white rabbits with short-term glucocorticoid application of fresh bone allograft vascular reconstruction problem was studied, the results showed that: allogeneic bone marrow cavity Lateral vascular remodeling is achieved primarily by ingrowth of the adjacent host osteogenic vessels. The cortical bone is mainly through the bone, adventitia lateral vascular penetration and the re-occupation of the original Harvard blood vessels and achieve. In the meantime, there are some early and early Harvard recanalization. (2) Under the conditions of short-term immunosuppression, the rate of revascularization is almost the same in allograft and autologous bone graft. (3) Vascular remodeling is the precursor of bone formation, Osteogenesis occurs and regulates the process of osteogenesis.Vascular infiltration from different sources and under different conditions may have different effects on the formation and absorption of bone.