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目的分析研究2型糖尿病采取甘精胰岛素联合格列美脲及阿卡波糖共同治疗的临床效果。方法选取2011年8月—2014年4月在该院接收的患有2型糖尿病的病人一共有114例,随机分为研究组、对照组,对照组对病人采取甘精胰岛素联合格列美脲治疗,研究组对病人采取甘精胰岛素联合阿卡波糖治疗,对研究组与对照组病人治疗效果给予分析研究。结果两组病人的空腹血糖、餐后2 h血糖、平均血糖、最高血糖以及Hb Alc水平都有明显降低,其中研究组餐后2 h血糖下降明显高于对照组(P<0.05);治疗3个月以后,研究组病人空腹血糖、餐后2 h血糖以及Hb Alc水平达标率明显高于对照组;研究组低血糖发生率明显低于对照组(P<0.05)。结论 2型糖尿病采取甘精胰岛素联合阿卡波糖共同治疗,可以使病人血糖控制在有效范围之内,以及低血糖发生率明显减少,具有临床推广价值。
Objective To study the clinical effect of glargine combined with glimepiride and acarbose on type 2 diabetes mellitus. Methods A total of 114 patients with type 2 diabetes who were admitted to the hospital from August 2011 to April 2014 were randomly divided into study group, control group and control group. The patients received glargine and glimepiride Treatment, the study group to patients with insulin glargine combined with acarbose treatment, the study group and control group of patients treated with the analysis. Results The fasting blood glucose, postprandial 2-h blood glucose, mean blood glucose, maximal blood glucose and Hb Alc levels were significantly decreased in both groups. The blood glucose level of the study group at 2 h after meal was significantly higher than that of the control group (P <0.05) Months later, the compliance rate of fasting blood glucose, postprandial 2-hour blood glucose and Hb Alc level in study group was significantly higher than that in control group. The incidence of hypoglycemia in study group was significantly lower than that in control group (P <0.05). Conclusion Type 2 diabetes treated with insulin glargine combined with acarbose, can make the patient’s blood glucose control within the effective range, and the incidence of hypoglycemia significantly reduced, with clinical value.