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目的了解广东增城地区成人健康体检脂肪肝患病现况及相关因素,为脂肪肝防治提供可靠依据。方法入选2221例广州增城地区单位干部职工,包括公安、法院、政府部门、税务局、交通局、银行系统的工作人员,分别检测血尿酸、超重/肥胖、高血压、空腹血糖(FPG)、总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、胆红素、转氨酶、乙肝两对半以及行肝脏B超检查。结果 2221例体检人群中发现脂肪肝162例,患病率为7.3%。Pearson相关分析示脂肪肝与超重/肥胖、高血压、高TC、高TG、高LDL-C、FPG异常、性别(男性)、转氨酶异常呈正相关(P<0.05)。多因素非条件Logistic回归示,超重/肥胖、高血压、高TG、高尿酸血症是脂肪肝的危险因素。结论广东增城地区干部职工的脂肪肝患病率与国内其他地区相当;超重/肥胖、高血压、血脂代谢异常、高尿酸血症是脂肪肝的危险因素,必须防治超重/肥胖、高血压、血脂代谢紊乱、高尿酸血症。
Objective To understand the prevalence and related factors of fatty liver in adults in Zengcheng, Guangdong Province, and to provide a reliable basis for the prevention and treatment of fatty liver. Methods Totally 2221 cadres and workers in Zengcheng district of Guangzhou were enrolled, including public security department, court, government departments, taxation bureau, transportation bureau and bank system staffs. The levels of serum uric acid, overweight / obesity, hypertension, fasting blood glucose (FPG) Cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), bilirubin, transaminase, hepatitis B two and a half and liver biopsy. Results A total of 162 cases of fatty liver were found in 2221 medical examination population, the prevalence was 7.3%. Pearson correlation analysis showed that there was a positive correlation between fatty liver and overweight / obesity, hypertension, high TC, high TG, high LDL-C, FPG abnormalities, gender (male) and aminotransferase abnormalities (P <0.05). Multivariate non-conditional logistic regression showed that overweight / obesity, hypertension, hyper TG, hyperuricemia were risk factors for fatty liver. Conclusion The prevalence of fatty liver in cadres and workers in Zengcheng, Guangdong Province is quite similar to that in other parts of the country. Overweight / obesity, hypertension, dyslipidemia and hyperuricemia are the risk factors of fatty liver. Overweight / obesity, hypertension, Metabolic disorders, hyperuricemia.