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目的观察慢性特发性血小板减少性紫癜(CITP)患者体内 T 淋巴细胞的活化情况和 CD4~+T淋巴细胞表面CD154的表达率,探讨细胞免疫和 CD154-CD40途径在CITP 发病中的作用,为临床治疗新途径提供试验依据。方法将20例 CITP 患者分为 A 组(发病后未治疗或未正规治疗者)和 B 组(复发难治者)。采用常规方法采取外周
Objective To investigate the activation of T lymphocytes in patients with chronic idiopathic thrombocytopenic purpura (CITP) and the expression of CD154 on CD4 ~ + T lymphocytes, and to explore the role of cellular immunity and CD154-CD40 pathway in the pathogenesis of CITP. New ways to provide experimental basis for clinical treatment. Methods Twenty patients with CITP were divided into group A (untreated or not treated) and group B (refractory relapse). Peripherals are routinely taken