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本试验按照前瞻、随机和双盲的方式进行,以给药治疗前至出院前(发病后10～14日)左室射血分数(LVEF)的改变作为主要观察终点。对象为在发病后12小时内(6.3±2.7小时)接受治疗的393例急性心肌梗塞病人,且至少随访2年。首先按照发病至开始治疗的时间分成:A 组<2小时,B 组2～12小时。然后再随机分成四组:前三组冠(状动)脉内灌注药物75～120分钟,依照所给药物的不同分别为 SK 组97例(链激酶2000U/min)、NTG 组99例(硝酸甘油0.01mg/min)和
The trial was conducted in a prospective, randomized, and double-blind manner using the change in left ventricular ejection fraction (LVEF) before treatment (10-14 days after onset) before treatment as the primary end point. Subjects were 393 acute myocardial infarction patients treated within 12 hours (6.3 ± 2.7 hours) after the onset of disease and were followed up for at least 2 years. First, according to the onset of treatment time is divided into: A group <2 hours, B group 2 to 12 hours. Then randomly divided into four groups: the first three coronary perfusion (coronary artery) infusion of 75 to 120 minutes, according to the different drugs were SK group 97 cases (streptokinase 2000U / min), NTG group 99 cases (nitric acid Glycerol 0.01 mg / min) and