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在成体金黄地鼠的视网膜上移植一段自体坐骨神经1～4个月后,视网膜神经节细胞纤维长入移植的坐骨神经中长达2 cm。具有再生纤维的神经节细胞分布于外周神经插入处与视网膜边缘之间的扇形或带状区域内。细胞数目与插入处的位置有关,接近视神经乳头处较远离视神经乳头处标记细胞数量多。移植后的视网膜标记神经元细胞体面积分布直方图表明:具有再生纤维的神经元胞体面积范围除包括正常大小的神经节细胞外,还包括相当多的胞体增大的神经元。用荧光染料核黄施于视束、真蓝施于移植的坐骨神经后的逆行荧光双标记法实验表明,再生的轴突起源于神经节细胞的损伤轴突,而不是完整神经节细胞轴突的侧芽。
Retinal ganglion cells grow into the sciatic nerve as long as 2 cm after transplantation of an autologous sciatic nerve for 1 to 4 months on the retina of adult golden hamster. Ganglion cells with regenerated fibers are distributed in the fan-shaped or band-shaped regions between the periphery of the peripheral nerve and the edge of the retina. The number of cells and the location of the insertion, near the optic disc more distant from the optic disc at the marked number of cells. Histogram of the retinal-labeled neuronal cell body area after transplantation showed that the range of neuronal soma with regenerated fibers included a considerable number of neurons with increased body cells in addition to normal-sized ganglion cells. Retrograde fluorometric double labeling assay using fluorescent dye nuclear yellow applied to the optic tract and true blue applied to the transplanted sciatic nerve showed that regenerated axons originate from damaged axons of ganglion cells but not from intact ganglion cells lateral bud.