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唾液中的硫氰酸盐是机体摄人氰化物后的解毒分解产物,唾液中该物质的浓度高于血清中。因为吸烟时,唾液中的硫氰酸盐浓度高,所以都把血浆中的尼古丁、可铁宁(Cotinine)及呼出气中的CO浓度共同作为吸烟的指标。因此作者从吸烟量、纸烟中HCN浓度与吸烟者和非吸烟者唾液中硫氰酸盐浓度间的关系进行研究以探讨它在作为吸烟者接触HCN的指标上的意义。以成人330名(吸烟者220名,非吸烟者110名)为研究对象,调查吸烟量。采取混合唾液3 ml,用改进的Bowler法测定其中硫氰酸盐含量。同时用Tedlar袋采集市售6种纸烟的烟雾,用SB型检测管测烟中的HCN,用UH型检测管测烟中的CO。8名
Thiocyanate in saliva is the body’s detoxification products after ingestion of cyanide decomposition products, saliva in the concentration of the substance higher than serum. Because of the high concentration of thiocyanate in saliva during smoking, both nicotine, cotinine in plasma and CO concentration in exhaled air are used as indicators of smoking. The authors therefore investigated the relationship between HCN concentration in cigarette smoke and thiocyanate concentration in sputum and non-smoker saliva to investigate its significance as an indicator of HCN exposure in smokers. A total of 330 adults (220 smokers and 110 non-smokers) were enrolled in this study to investigate the prevalence of smoking. Take 3 ml of mixed saliva and determine thiocyanate content using the modified Bowler method. At the same time, Tedlar bags were used to collect the smoke of commercially available 6 cigarettes, HCN in the SB type test tube and CO in the cigarette with the UH type test tube. 8 people