目的　中草药及复方抗乙肝病毒s、e抗原的实验研究及疗效观察。方法　应用反向被动血凝抑制 (RPHI)法和酶联免疫吸附检测 (ELISA)法筛选出抗HBsAg高效中草药组成复方。 结果　服用 2个疗程e抗原阴转率 5 1% ,与干扰素疗效相似 ,服用 4个疗程则可明显提高疗效。结论　中草药复方辩证治疗慢性乙肝 ,对HBsAg、HBeAg、HBV DNA转阴 ,抗HBs、抗HBe转阳取得了较好的疗效 ,长期服用可防止复发 Objective To study the curative effect and curative effect of traditional Chinese medicine and compound anti-hepatitis B virus s and e antigen. Methods The compound anti-HBsAg-efficient Chinese herbal medicine was screened by reverse passive hemagglutination inhibition (RPHI) and enzyme-linked immunosorbent assay (ELISA). The results of taking two courses of e antigen negative conversion rate of 51%, with similar efficacy of interferon, taking 4 courses can significantly improve the efficacy. Conclusion Chinese herbal compound dialectical treatment of chronic hepatitis B, HBsAg, HBeAg, HBV DNA negative, anti-HBs, anti-HBe turn positive achieved good results, long-term use to prevent recurrence