一、抗精神病药物1.酚噻嗪类:在精神科应用最广的氯丙嗪(CPZ)对视觉器官可引起早发性和晚发性副作用。CPZ 治疗第1周或其后急剧增量,可产生伴有锥外系障碍的动眼危象。高剂量 CPZ增加视觉器官对光的敏感性,易引起日光性眼灼伤。日服 CPZ2000mg 可造成角膜上皮急性损伤。以往报导的 CPZ 晚发性并发症如晶体和角膜色素沉着有减少趋向,但近来的临 First, antipsychotics 1. Phenothiazines: The most widely used psychotropic chlorpromazine (CPZ) on the visual organs can cause early and late side effects. The sharp increase in the first or subsequent week after CPZ treatment can produce eye-movement crisis associated with extrapyramidal disorders. High-dose CPZ increases the sensitivity of visual organs to light, can cause solar eye burns. Japanese clothing CPZ2000mg can cause acute corneal epithelial injury. Previously reported late complications of CPZ such as crystalline and corneal pigmentation tended to decrease, but recent