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目的:探讨高脂血症者慢性肾脏病的患病情况及相关危险因素。方法:对2009—2010年成都铁路职工健康体检中有完整资料的2 578例高脂血症者慢性肾脏病的患病情况及相关危险因素进行分析。结果:高脂血症者白蛋白尿、血尿和肾功能下降的患病率分别为14.08%、2.37%和3.26%。该人群中慢性肾脏病的患病率为17.73%;高脂血症者胆固醇、三酰甘油均与尿微量白蛋白/肌酐比值呈正直线相关;女性、高血压、糖尿病、高尿酸、高三酰甘油和高体质量指数是高脂血症者慢性肾脏病的独立危险因素。结论:高脂血症者中,慢性肾脏病的患病率较普通人群高,主要表现为白蛋白尿,与血脂水平有关。控制血脂、血压、血糖、血尿酸和体质量指数,可减少慢性肾脏病的发生和发展。
Objective: To investigate the prevalence and related risk factors of chronic kidney disease in patients with hyperlipidemia. Methods: The prevalence and related risk factors of chronic kidney disease in 2 578 cases of hyperlipidemia with complete data from 2009 to 2010 in the health examination of Chengdu railway workers were analyzed. Results: The prevalences of albuminuria, hematuria and renal dysfunction in hyperlipidemic patients were 14.08%, 2.37% and 3.26% respectively. The prevalence of chronic kidney disease in this population was 17.73%; cholesterol and triglyceride in hyperlipidemia were positively correlated with urinary albumin / creatinine; women, hypertension, diabetes, hyperuricemia, And high body mass index are independent risk factors for chronic kidney disease in patients with hyperlipidemia. Conclusion: The prevalence of chronic kidney disease in hyperlipidemia patients is higher than that in the general population, mainly as albuminuria, which is related to blood lipid levels. Control of blood lipids, blood pressure, blood glucose, blood uric acid and body mass index can reduce the incidence of chronic kidney disease and development.