报告29例韦氏肉芽肿。起病部位主要在上呼吸道(96.5%),以鼻腔为多,故便于借活检作早期诊断。病程中受侵犯的器官依次有肾93%,眼44.8%及肺33.2%等。病理变化有:小动静脉和毛细血管炎;上皮样细胞肉芽肿,细胞散在,不形成典型的上皮样结节,无干酪样坏死;常有多核巨细胞,其分布与血管炎和肉芽肿无规律性的关系。1例兼有肉芽肿和恶性组织细胞浸润。 Report of 29 cases of Wechsler’s granulomatosis. The main part of the disease in the upper respiratory tract (96.5%), to the nasal cavity and more, it is easy to take early diagnosis by biopsy. During the course of the affected organs were followed by 93% of the kidneys, 44.8% of eyes and lung 33.2% and so on. Pathological changes are: arteriovenous and capillary inflammation; epithelioid cell granuloma, scattered cells, do not form a typical epithelioid nodules, caseous necrosis; often multinucleated giant cells, and its distribution and vasculitis and granuloma no Regular relationship. 1 case of both granuloma and malignant cell infiltration.