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目的:观察单片复方制剂在社区高血压病的血压管理中的应用。方法:常州市天宁区茶山街道居民中选取高血压病患者,其中接受单片复方制剂患者300人,接受多片联合方案312人,服药前及服药一月后测量血压(收缩压、舒张压),对两组服药患者1、3、6月后进行随访,记录服药情况。结果:单片复方制剂组和多片联合组在服药一月后收缩压及舒张压较前均有下降(收缩压162.42±23.0、131.56±19.6,舒张压103.30±5.1、79.09±11.1),差异有统计学意义(P<0.05),6个月后单片复方制剂组服药率高于多片联合组,差异有统计学意义(P<0.05)。结论:单片复方制剂降压疗效等同于多片联合方案,但患者依从性高于多片联合方案。
Objective: To observe the application of monolithic compound in blood pressure management of community hypertension. Methods: Hypertension was selected among residents of Dasan Street, Tianning District, Changzhou City. Among them, 300 patients received monotherapy and 312 patients received combination therapy. Before and after taking medicine, blood pressure (systolic and diastolic blood pressure ), Two groups of patients taking medicine after 1, 3, 6 months follow-up, record medication situation. Results: The systolic blood pressure and diastolic blood pressure were decreased in the monotherapy group and the combined therapy group after one month’s treatment (systolic blood pressure 162.42 ± 23.0,131.56 ± 19.6, diastolic blood pressure 103.30 ± 5.1,79.09 ± 11.1) (P <0.05). After 6 months, the taking rate of monotherapy group was higher than multi-slice combination group, the difference was statistically significant (P <0.05). Conclusion: The antihypertensive effect of single-component compound is equivalent to multi-slice combination, but its compliance is higher than multi-slice combination.