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目的比较不同血液净化方式对维持血液透析患者甲状旁腺激素(PTH)的清除效果。方法对进行维持性血液透析患者30例随机分为血液灌流串联血液透析(HP+HD)组和血液透析(HD)组2组,观察透析前后患者PTH水平的情况。结果 (HP+HD)组和(HD)组PTH水平较透前均有下降,但(HP+HD)组下降明显,(HP+HD)组前后比较有统计学意义(P<0.05),(HD)组PTH水平前后比较无统计学意义(P>0.05)。结论血液灌流联合血液透析能有效清除尿毒症患者PTH水平,降低患者的患病率和死亡率。
Objective To compare the clearance effect of different blood purification methods on maintaining parathyroid hormone (PTH) in hemodialysis patients. Methods Thirty patients with maintenance hemodialysis were randomly divided into two groups: hemodialysis (HP + HD) group and hemodialysis (HD) group. The levels of PTH in patients before and after dialysis were observed. The levels of PTH in HP + HD group and HD group were significantly lower than those in HP + HD group (P <0.05) HD group PTH levels before and after comparison was not statistically significant (P> 0.05). Conclusion Hemoperfusion combined with hemodialysis can effectively remove PTH in uremic patients and reduce the morbidity and mortality of patients.