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长期以来,人们一直怀疑女性激素与脑膜瘤之间有某种联系。有文献报道与男性相比,女性患脑膜瘤的比例是男性的2～3倍。患脊膜瘤的比例是男性的9倍。早在1929年,Cushing等报道脑膜瘤患者在妊娠期症状恶化,继此报导后又有许多类似报道。脑膜瘤还与其它激素相关性肿瘤有关。本文首次报道一例女性患者皮下植入孕酮类避孕药物后致脑膜瘤生长加速的病例。
For a long time, people have always suspected that there is some connection between female hormone and meningioma. Reported in the literature compared with men, women suffering from meningioma is 2 to 3 times the proportion of men. The rate of suffering from meningioma is 9 times that of men. As early as 1929, Cushing et al reported that men with meningioma had worse symptoms during pregnancy and many similar reports were made after this report. Meningiomas are also associated with other hormone-related tumors. This is the first report of a case of female patients implanted subcutaneous progesterone contraceptives resulting in accelerated growth of meningioma cases.